Year 2019 / Volume 26 / Number 3

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Review

Pain in Parkinson's disease. A look at a little known aspect of this pathology

Rev. Soc. Esp. Dolor. 2019; 26(3): 184-198 / DOI: 10.20986/resed.2019.3733/2019

Julio Rotondo, Martín Toro, Marcos Bolívar, María Eugenia Seijas, Carmen Carrillo


ABSTRACT

Parkinson's disease (PD) is a neurodegenerative disease, the second most prevalent, after Alzheimer's disease. It presents both motor and non-motor symptoms; These include autonomic dysfunction, unexplained pain, cognitive impairment, anxiety, depression, among others. Some of these patients experience pain as an early symptom of Parkinson's, even before the expression of their disease. Among people who have PD and who experience pain, they describe it as a worrisome symptom, being a cause of suffering and disability. However, despite this, pain in PD often remains undiagnosed and untreated. Therefore, it is important to understand that pain can be part of the Parkinson's experience and learn ways to manage it.
This paper reviews current data on possible mechanisms, classifications, evolution, potential risk factors and pain control in PD. The mechanism of pain in this situation is complex, and is influenced by different factors, which may be linked to pathological changes in the anatomical structures involved in nociceptive mechanisms.



RESUMEN

La enfermedad de Parkinson (EP) es una enfermedad neurodegenerativa, la segunda con mayor prevalencia después de la enfermedad de Alzheimer. Presenta tanto síntomas motores como no motores; entre estos últimos se encuentran disfunción autonómica, dolor inexplicable, deterioro cognitivo, ansiedad, depresión, entre otros. Algunos de estos pacientes experimentan el dolor como un síntoma temprano de Parkinson, incluso antes de la expresión de su enfermedad. Entre las personas que tienen EP y que experimentan dolor, lo describen como un síntoma preocupante, siendo una causa de sufrimiento y de incapacidad. Sin embargo, a pesar de ello, el dolor en la EP a menudo permanece sin diagnóstico y sin tratamiento. Por tanto, es importante entender que el dolor puede ser parte de la experiencia del Parkinson y aprender las formas de manejarlo.
Este trabajo revisa datos actuales sobre posibles mecanismos, clasificaciones, evolución, factores de riesgo potenciales y control del dolor en la EP. El mecanismo del dolor en esta situación es complejo, y está influenciado por distintos factores, pudiendo estar vinculado a cambios patológicos en las estructuras anatómicas involucradas en mecanismos nociceptivos.





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Proctalgia and pudendal nerve entrapment: an association to know

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Consensus for the definition of post-mastectomy pain syndrome

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Radiofrequency thermal and splanchnics nerves block

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Farmacologic adyuvants with saving effect of opioids in the perioperative period

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Experience in two hospitals about the observation of pain responses in hospitalized preterm infants

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Platelet-rich plasma in treating peripheral neuropathic pain. Preliminary report

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Pain in the elderly and in patients with cognitive deficit. A DELPHI study

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Sex and pain: sexual satisfaction and sexual function in a sample of patients with chronic, non-pelvic pain

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Analgesic efficacy of topical sevoflurane on wounds

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Potential uses of Mirtazapine in palliative care beyond its antidepressant effect

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Pain management in cancer patients receiving radiotherapy: GORVAMUR study, a prospective, observational, epidemiological study

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Epidural analgesia vs. surgical wound analgesia to control acute post-operative pain in open colon surgery

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CAD-R. Chronic pain coping questionnaire: confirmatory factor analysis. Are there individual differences in gender, age and type of pain?

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Intervention of manual motor skill exercises on pain and functionality in adults subjects with rheumatoid arthritis: case series

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Characterization of chest pain in patients attending the emergency department of a high-complexity-level healthcare institution, during 2014-2015, in Medellín, Colombia

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Chronic pain: relationship with prefrontal symptoms and perceived stress

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The effectiveness of electrical spinal-cord stimulation in type i complex regional pain syndrome. A literature review

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Paxiflas®: new FDT combination of tramadol/paracetamol for treating moderate to severe pain

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Instrucciones para citar

Rotondo J, Toro M, Bolívar M, Seijas M, Carrillo C. Pain in Parkinson's disease. A look at a little known aspect of this pathology. Rev Soc Esp Dolor 2019; 26(3): 184-198 / DOI: 1020986/resed20193733/2019


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Estadísticas de Dimensions


Estadísticas de Plum Analytics

Ficha Técnica

Recibido: 29/03/2019

Aceptado: 05/04/2019

Prepublicado: 07/05/2019

Publicado: 28/05/2019

Tiempo de prepublicación: 39 días

Tiempo de edición del artículo: 60 días


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