Year 2021 / Volume 28 / Supplement 1

Abstract PDF HTML

Article Osteoarthritis Monographic

Experimental models for pain evaluation in osteoarthritis

Rev. Soc. Esp. Dolor. 2021; 28(13): 18-30 / DOI: 10.20986/resed.2021.3872/2020

José Antonio García, Esther Berrocoso, Juan Antonio Micó


ABSTRACT

Osteoarthritis (OA) is one of the main pathologies associated with chronic pain, and despite decades of study many key aspects of its pathophysiology are still unknown, which contributes to continuing to investigate therapeutic options capable of effectively and safely controlling pain. The use of experimental models of OA continues to be one of the most useful alternatives for understanding both the etiopathogenesis of OA and for the development of possible biomarkers and treatments. Despite the usefulness of experimental models in the advancement of knowledge of OA, there is no single model or technical procedure that allows us to study in it the great variety of structural and symptomatic changes that occur in the patient throughout his illness. However, today we have models and techniques for pain assessment that allow us to understand the mechanisms underlying OA as well as to understand and explore new therapeutic opportunities for its more effective and safe control.



RESUMEN

La osteoartritis (OA) es una de las principales patologías asociadas al dolor crónico y, a pesar de décadas de estudio, todavía se desconocen muchos aspectos clave de su fisiopatología, lo que impulsa a seguir investigando opciones terapéuticas capaces de controlar el dolor de manera eficaz y segura. El uso de modelos experimentales de OA sigue siendo una de las alternativas más útiles para la comprensión tanto de la etiopatogenia de la OA como para el desarrollo de posibles biomarcadores y tratamientos. A pesar de la utilidad de los modelos experimentales en el avance del conocimiento de la OA, no existe un modelo o procedimiento técnico único que nos permita estudiar en él la gran variedad de cambios estructurales y sintomáticos que suceden en el paciente a lo largo de su enfermedad. No obstante, hoy en día disponemos de modelos y técnicas para la evaluación del dolor que nos permiten comprender los mecanismos que subyacen en la OA, así como comprender y explorar nuevas oportunidades terapéuticas para su control más eficaz y seguro.





Complete Article

Nuevo comentario

Security code:
CAPTCHA code image
Speak the codeChange the code
 

Comentarios

No comments in this article

Bibliografía

1. World Health Organization. Osteoarthritis. Chapter 6.12 [Internet]. In: Priority diseases and reasons for inclusion. Disponible en: https://www.who.int/medicines/areas/priority_medicines/prior_med_ch6_12/en/
2. Haq I, Murphy E, Dacre J. Osteoarthritis. Postgrad Med J. 2003;79(933):377-83. DOI: 10.1136/pmj.79.933.377.
DOI: 10.1136/pmj.79.933.377
3. Miller RE, Malfait AM. Osteoarthritis pain: What are we learning from animal models? Best Pract Res Clin Rheumatol. 2017;31(5):676-87. DOI: 10.1016/j.berh.2018.03.003.
DOI: 10.1016/j.berh.2018.03.003
4. Global Burden of Disease Study 2013 Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015;386(9995):743-800. DOI: 10.1016/S0140-6736(15)60692-4.
DOI: 10.1016/S0140-6736(15)60692-4
5. Laupattarakasem W, Laopaiboon M, Laupattarakasem P, Sumananont C. Arthroscopic debridement for knee osteoarthritis. Cochrane Database Syst Rev. 2008;(1):CD005118. DOI: 10.1002/14651858.CD005118.pub2.
DOI: 10.1002/14651858.CD005118.pub2
6. Malfait AM, Schnitzer TJ. Towards a mechanism-based approach to pain management in osteoarthritis. Nat Rev Rheumatol. 2013;9(11):654-64. DOI: 10.1038/nrrheum.2013.138.
DOI: 10.1038/nrrheum.2013.138
7. Crichton B, Green M. GP and patient perspectives on treatment with non-steroidal anti-inflammatory drugs for the treatment of pain in osteoarthritis. Curr Med Res Opin. 2002;18(2):92-6. DOI: 10.1185/030079902125000345.
DOI: 10.1185/030079902125000345
8. Matthews GL. Disease modification: promising targets and impediments to success. Rheum Dis Clin North Am. 2013;39(1):177-87. DOI: 10.1016/j.rdc.2012.10.006.
DOI: 10.1016/j.rdc.2012.10.006
9. Haviv B, Bronak S, Thein R. The complexity of pain around the knee in patients with osteoarthritis. Sat. 2013;5(4):178-81.
10. Teeple E, Jay GD, Elsaid KA, Fleming BC. Animal models of osteoarthritis: challenges of model selection and analysis. AAPS J. 2013;15(2):438-46. DOI: 10.1208/s12248-013-9454-x.
DOI: 10.1208/s12248-013-9454-x
11. Piel MJ, Kroin JS, van Wijnen AJ, Kc R, Im HJ. Pain assessment in animal models of osteoarthritis. Gene. 2014;537(2):184-8. DOI: 10.1016/j.gene.2013.11.091.
DOI: 10.1016/j.gene.2013.11.091
12. N D'Souza W, Y Ng G, D Youngblood B, Tsuji W, G Lehto S. A review of current animal models of osteoarthritis pain. Curr Pharm Biotechnol. 2011;12(10):1596-612. DOI: 10.2174/138920111798357320.
DOI: 10.2174/138920111798357320
13. McGonigle P, Ruggeri B. Animal models of human disease: challenges in enabling translation. Biochem Pharmacol. 2014;87(1):162-71. DOI: 10.1016/j.bcp.2013.08.006.
DOI: 10.1016/j.bcp.2013.08.006
14. Nestler EJ, Hyman SE. Animal models of neuropsychiatric disorders. Nat Neurosci 2010;13(10):1161-9. DOI: 10.1038/nn.2647.
DOI: 10.1038/nn.2647
15. Brown DC. What can we learn from osteoarthritis pain in companion animals? Clin Exp Rheumatol 2017;107(5):53-8.
16. McCoy AM. Animal models of osteoarthritis: comparisons and key considerations. Vet Pathol. 2015;52(5):803-18. DOI: 10.1177/0300985815588611.
DOI: 10.1177/0300985815588611
17. O’Brien M, Philpott HT, McDougall JJ. Understanding osteoarthritis pain through animal models. Clin Exp Rheumatol. 2017;35 Suppl 107(5):47-52.
18. Jimenez PA, Glasson SS, Trubetskoy OV, Haimes HB. Spontaneous osteoarthritis in Dunkin Hartley guinea pigs: histologic, radiologic, and biochemical changes. Comparative Med. 1997;47(6):598-601.
19. Lampropoulou-Adamidou K, Lelovas P, Karadimas EV, Liakou C, Triantafillopoulos IK, Dontas I, et al. Useful animal models for the research of osteoarthritis. Eur J Orthop Surg Traumatol. 2014;24(3):263-71. DOI: 10.1007/s00590-013-1205-2.
DOI: 10.1007/s00590-013-1205-2
20. Vincent T. L., Williams R. O., Maciewicz R., Silman A., Garside P. for the Arthritis Research UK animal Models Working Group. Mapping pathogenesis of arthritis through small animal models. Rheumatology. 2012; 51(11), 1931-1941. DOI:10.1093/rheumatology/kes035.
DOI: 10.1093/rheumatology/kes035
21. Staines KA, Poulet B, Wentworth DN, Pitsillides AA. The STR/ort mouse model of spontaneous osteoarthritis–an update. Osteoarthritis and cartilage. 2017;25(6):802-8. DOI: 10.1016/j.joca.2016.12.014.
DOI: 10.1016/j.joca.2016.12.014
22. Berenbaum F, Griffin TM, Liu-Bryan R. Metabolic regulation of inflammation in osteoarthritis. Arthritis Rheum. 2017;69(1):9.
DOI: 10.1002/art.39842
23. Oliveria SA, Felson DT, Cirillo PA, Reed JI, Walker AM. Body weight, body mass index, and incident symptomatic osteoarthritis of the hand, hip, and knee. Epidemiology. 1999;10(2):161-6.
DOI: 10.1097/00001648-199903000-00013
24. Grotle M, Hagen KB, Natvig B, Dahl FA, Kvien TK. Obesity and osteoarthritis in knee, hip and/or hand: an epidemiological study in the general population with 10 years follow-up. BMC Musculoskelet Disord. 2008;9:132. DOI: 10.1186/1471-2474-9-132.
DOI: 10.1186/1471-2474-9-132
25. Griffin TM, Fermor B, Huebner JL, Kraus VB, Rodriguiz RM, Wetsel WC, et al. Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice. Arthritis Res Ther. 2010;12(4):R130. DOI: 10.1186/ar3068.
DOI: 10.1186/ar3068
26. Ramzan I, Wong BK, Corcoran GB. Pain sensitivity in dietary-induced obese rats. Physiol Behav. 1993;54(3):433-5. DOI: 10.1016/0031-9384(93)90231-4.
DOI: 10.1016/0031-9384(93)90231-4
27. Okifuji A, Hare BD. The association between chronic pain and obesity. J Pain Res. 2015; 8:399-408. DOI: 10.2147/JPR.S55598.
DOI: 10.2147/JPR.S55598
28. Zimmermann M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain. 1983;16(2):109-10. DOI: 10.1016/0304-3959(83)90201-4.
DOI: 10.1016/0304-3959(83)90201-4
29. Bendele AM. Animal models of osteoarthritis. J Musculoskelet Neuronal Interact. 2001;1(4):363-76.
30. Cope P. J., Ourradi K., Li Y., Sharif, M. Models of osteoarthritis: the good, the bad and the promising. Osteoarthr. Cartil. 2019; 27(2), 230-239. DOI: 10.1016/l.joca.2018.09.016
31. Blaker CL, Clarke EC, Little CB. Using mouse models to investigate the pathophysiology, treatment, and prevention of post‐traumatic osteoarthritis. J Orthop Res. 2017;35(3):424-39. DOI: 10.1002/jor.23343.
DOI: 10.1002/jor.23343
32. Bove SE, Calcaterra SL, Brooker RM, Huber CM, Guzman RE, Juneau PL, et al. Weight bearing as a measure of disease progression and efficacy of anti-inflammatory compounds in a model of monosodium iodoacetate-induced osteoarthritis. Osteoarthritis Cartilage. 2003;11(11):821-30. DOI: 10.1016/s1063-4584(03)00163-8.
DOI: 10.1016/S1063-4584(03)00163-8
33. Combe R, Bramwell S, Field MJ. The monosodium iodoacetate model of osteoarthritis: a model of chronic nociceptive pain in rats? Neurosci Lett. 2004;370(2-3):236-40. DOI: 10.1016/j.neulet.2004.08.023.
DOI: 10.1016/j.neulet.2004.08.023
34. McDougall JJ, Albacete S, Schuelert N, Mitchell PG, Lin C, Oskins JL, et al. Lysophosphatidic acid provides a missing link between osteoarthritis and joint neuropathic pain. Osteoarthritis Cartilage. 2017;25(6):926-34. DOI: 10.1016/j.joca.2016.08.016.
DOI: 10.1016/j.joca.2016.08.016
35. Mototani H, Iida A, Nakajima M, Furuichi T, Miyamoto Y, Tsunoda T, et al. A functional SNP in EDG2 increases susceptibility to knee osteoarthritis in Japanese. Hum Mol Genet. 2008;17(12):1790-7. DOI: 10.1093/hmg/ddn069.
DOI: 10.1093/hmg/ddn069
36. Rüger B, Giurea A, Wanivenhaus AH, Zehetgruber H, Hollemann D, Yanagida G, et al. Endothelial precursor cells in the synovial tissue of patients with rheumatoid arthritis and osteoarthritis. Arthritis Rheum. 2004;50(7):2157-66. DOI: 10.1002/art.20506.
DOI: 10.1002/art.20506
37. Weng LH, Ko JY, Wang CJ, Sun YC, Wang FS. Dkk‐1 promotes angiogenic responses and cartilage matrix proteinase secretion in synovial fibroblasts from osteoarthritic joints. Arthritis Rheum. 2012;64(10):3267-77. DOI: 10.1002/art.34602.
DOI: 10.1002/art.34602
38. Little CB, Hunter DJ. Post-traumatic osteoarthritis: from mouse models to clinical trials. Nat Rev Rheumatol. 2013;9(8):485-97. DOI: 10.1038/nrrheum.2013.72.
DOI: 10.1038/nrrheum.2013.72
39. Poole R, Blake S, Buschmann M, Goldring S, Laverty S, Lockwood S, et al. Recommendations for the use of preclinical models in the study and treatment of osteoarthritis. Osteoarthritis Cartilage. 2010;18:S10-S16. DOI: 10.1016/j.joca.2010.05.027.
DOI: 10.1016/j.joca.2010.05.027
40. Kuyinu EL, Narayanan G, Nair LS, Laurencin CT. Animal models of osteoarthritis: classification, update, and measurement of outcomes. J Orthop Surg Res. 2016;11:19. DOI: 10.1186/s13018-016-0346-5.
DOI: 10.1186/s13018-016-0346-5
41. Christiansen BA, Guilak F, Lockwood KA, Olson SA, Pitsillides AA, Sandell LJ, et al. Non-invasive mouse models of post-traumatic osteoarthritis. Osteoarthritis Cartilage. 2015;23(10):1627-38. DOI: 10.1016/j.joca.2015.05.009.
DOI: 10.1016/j.joca.2015.05.009
42. Gabriel AF, Honig WMM, Marcus MAE, Joosten EAJ. Measuring pain-induced gait adaptation: The CatWalk method. J Neurosci Methods. 2007;163(1):9-16. DOI: 10.1016/j.jneumeth.2007.02.003.
DOI: 10.1016/j.jneumeth.2007.02.003
43. Fernihough J, Gentry C, Malcangio M, Fox A, Rediske J, Pellas T, et al. Pain related behaviour in two models of osteoarthritis in the rat knee. Pain. 2004;112(1-2):83-93. DOI: 10.1016/j.pain.2004.08.004.
DOI: 10.1016/j.pain.2004.08.004
44. Kang M, Jung I, Hur J, Kim SH, Lee JH, Kang JY, et al. The analgesic and anti-inflammatory effect of WIN-34B, a new herbal formula for osteoarthritis composed of Lonicera japonica Thunb and Anemarrhena asphodeloides BUNGE in vivo. J. Ethnopharmacol. 2010;131(2):485-96. DOI: 10.1016/j.jep.2010.07.025.
DOI: 10.1016/j.jep.2010.07.025
45. Chaplan SR, Bach FW, Pogrel JW, Chung JM, Yaksh TL. Quantitative assessment of tactile allodynia in the rat paw. J. Neurosci. Methods. 1994;53(1):55-63. DOI: 10.1016/0165-0270(94)90144-9.
DOI: 10.1016/0165-0270(94)90144-9
46. Randall LO, Selitto J. A method for measurement of analgesic activity on inflamed tissues. Arch Int Pharmacodyn. 1957;111(4):409-19.
47. Dubois MY, Gallagher RM, Lippe PM. Pain medicine position paper. Pain Med. 2009;10(6):972-1000. DOI: 10.1111/j.1526-4637.2009.00696.x.
DOI: 10.1111/j.1526-4637.2009.00696.x
48. Driscoll C, Chanalaris A, Knights C, Ismail H, Sacitharan PK, Gentry C, et al. Nociceptive sensitizers are regulated in damaged joint tissues, including articular cartilage, when osteoarthritic mice display pain behavior. Arthritis Rheumatol. 2016;68(4):857-67. DOI: 10.1002/art.39523.
DOI: 10.1002/art.39523
49. Vonsy JL, Ghandehari J, Dickenson AH. Differential analgesic effects of morphine and gabapentin on behavioural measures of pain and disability in a model of osteoarthritis pain in rats. Eur J Pain. 2009;13(8):786-93. DOI: 10.1016/j.ejpain.2008.09.008.
DOI: 10.1016/j.ejpain.2008.09.008
50. Woolfe G, MacDonald AD. The evaluation of the analgesic action of pethidine hydrochloride (Demerol). J Pharmacol Exp Ther. 1944;80(3):300-7.
51. Deuis JR, Dvorakova LS, Vetter I. Methods used to evaluate pain behaviors in rodents. Front Mol Neurosci. 2017;10:284. DOI: 10.3389/fnmol.2017.00284.
DOI: 10.3389/fnmol.2017.00284
52. Espejo EF, Mir D. Structure of the rat's behaviour in the hot plate test. Behav Brain Res. 1993;56(2):171-6. DOI: 10.1016/0166-4328(93)90035-o.
DOI: 10.1016/0166-4328(93)90035-O
53. Hargreaves K, Dubner R, Brown F, Flores C, Joris J. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain. 1988;32(1):77-88. DOI: 10.1016/0304-3959(88)90026-7.
DOI: 10.1016/0304-3959(88)90026-7
54. Deuis JR, Vetter I. The thermal probe test: A novel behavioral assay to quantify thermal paw withdrawal thresholds in mice. Temperature. 2016;3(2):199-207. DOI: 10.1080/23328940.2016.1157668.
DOI: 10.1080/23328940.2016.1157668
55. Carlton SM, Lekan HA, Kim SH, Chung JM. Behavioral manifestations of an experimental model for peripheral neuropathy produced by spinal nerve ligation in the primate. Pain. 1994;56(2):155-66. DOI: 10.1016/0304-3959(94)90090-6.
DOI: 10.1016/0304-3959(94)90090-6
56. Jacobs BY, Kloefkorn HE, Allen KD. Gait analysis methods for rodent models of osteoarthritis. Curr Pain Headache Rep. 2014;18(10):456. DOI: 10.1007/s11916-014-0456-x.
DOI: 10.1007/s11916-014-0456-x
57. Griffioen MA, Dernetz VH, Yang GS, Griffith KA, Dorsey SG, Renn CL. Evaluation of dynamic weight bearing for measuring non evoked inflammatory hyperalgesia in mice. Nurs Res. 2015;64(2):81-7. DOI: 10.1097/NNR.0000000000000082.
DOI: 10.1097/NNR.0000000000000082
58. Berryman ER, Harris RL, Moalli M, Bagi CM. Digigait quantitation of gait dynamics in rat rheumatoid arthritis model. J Musculoskelet Neuronal Interact. 2009;9(2):89-98.
59. Parvathy SS, Masocha W. Gait analysis of C57BL/6 mice with complete Freund's adjuvant-induced arthritis using the CatWalk system. BMC Musculoskelet Disord. 2013;14(1):14. DOI: 10.1186/1471-2474-14-14.
DOI: 10.1186/1471-2474-14-14
60. Adams BL, Guo W, Gors RT, Knopp KL. Pharmacological interrogation of a rodent forced ambulation model: leveraging gait impairment as a measure of pain behaviour pre-clinically. Osteoarthritis Cartilage. 2016;24(11):1928-39. DOI: 10.1016/j.joca.2016.05.022.
DOI: 10.1016/j.joca.2016.05.022
61. Schött E, Berge OG, Ängeby-Möller K, Hammarström G, Dalsgaard CJ, Brodin E. Weight bearing as an objective measure of arthritic pain in the rat. J Pharmacol Toxicol Methods. 1994;31(2):79-83. DOI: 10.1016/1056-8719(94)90046-9.
DOI: 10.1016/1056-8719(94)90046-9
62. Gaston-Johansson F, Albert M, Fagan E, Zimmerman L. Similarities in pain descriptions of four different ethnic-culture groups. J. Pain Symptom Manage. 1990;5(2):94-100. DOI: 10.1016/s0885-3924(05)80022-3.
DOI: 10.1016/S0885-3924(05)80022-3
63. Wibbenmeyer L, Sevier A, Liao J, Williams I, Latenser B, Lewis 2nd R, et al. Evaluation of the usefulness of two established pain assessment tools in a burn population. J Burn Care Res. 2011;32(1):52-60. DOI: 10.1097/BCR.0b013e3182033359.
DOI: 10.1097/BCR.0b013e3182033359
64. Tappe‐Theodor A, Kuner R. Studying ongoing and spontaneous pain in rodents–challenges and opportunities. Eur J Neurosci. 2014;39(11):1881-90. DOI: 10.1111/ejn.12643.
DOI: 10.1111/ejn.12643
65. Mogil JS. Animal models of pain: progress and challenges. Nat. Rev. Neurosci. 2009;10(4):283-94. DOI: 10.1038/nrn2606.
DOI: 10.1038/nrn2606
66. Jirkof P, Cesarovic N, Rettich A, Nicholls F, Seifert B, Arras M. Burrowing behavior as an indicator of post-laparotomy pain in mice. Front Behav Neurosci. 2010;4:165. DOI: 10.3389/fnbeh.2010.00165.
DOI: 10.3389/fnbeh.2010.00165
67. Bryden LA, Nicholson JR, Doods H, Pekcec A. Deficits in spontaneous burrowing behavior in the rat bilateral monosodium iodoacetate model of osteoarthritis: an objective measure of pain-related behavior and analgesic efficacy. Osteoarthritis Cartilage. 2015;23(9):1605-12. DOI: 10.1016/j.joca.2015.05.001.
DOI: 10.1016/j.joca.2015.05.001
68. Deacon RM. Burrowing in rodents: a sensitive method for detecting behavioral dysfunction. Nat Protoc. 2006;1(1):118-21. DOI: 10.1038/nprot.2006.19.
DOI: 10.1038/nprot.2006.19
69. Liu P, Okun A, Ren J, Guo R, Ossipov MH, Xie J, King T, Porreca F, et al. Ongoing pain in the MIA model of osteoarthritis. Neurosci Lett. 2011;493(3):72-5. DOI: 10.1016/j.neulet.2011.01.027.
DOI: 10.1016/j.neulet.2011.01.027
70. Navratilova E, Porreca F. Reward and motivation in pain and pain relief. Nat Neurosci. 2014;17(10):1304-12. DOI: 10.1038/nn.3811.
DOI: 10.1038/nn.3811
71. King T, Vera-Portocarrero L, Gutierrez T, Vanderah TW, Dussor G, Lai J, et al. Unmasking the tonic-aversive state in neuropathic pain. Nat Neurosci. 2009;12(11):1364-6. DOI: 10.1038/nn.2407.
DOI: 10.1038/nn.2407
72. Brodkin J, Frank D, Grippo R, Hausfater M, Gulinello M, Achterholt N, et al. Validation and implementation of a novel high-throughput behavioral phenotyping instrument for mice. J Neurosci Methods. 2014;224:48-57. DOI: 10.1016/j.jneumeth.2013.12.010.
DOI: 10.1016/j.jneumeth.2013.12.010
73. Langford DJ, Bailey AL, Chanda ML, Clarke SE, Drummond TE, Echols S, et al. Coding of facial expressions of pain in the laboratory mouse. Nat Methods. 2010;7(6):447-9. DOI: 10.1038/nmeth.1455.
DOI: 10.1038/nmeth.1455
74. Schuelert N, McDougall JJ. Grading of monosodium iodoacetate-induced osteoarthritis reveals a concentration-dependent sensitization of nociceptors in the knee joint of the rat. Neurosci. Lett. 2009;465(2):184-8. DOI: 10.1016/j.neulet.2009.08.063.
DOI: 10.1016/j.neulet.2009.08.063
75. Johnson CI, Argyle DJ, Clements DN. In vitro models for the study of osteoarthritis. Vet J. 2016;209:40-9. DOI: 10.1016/j.tvjl.2015.07.011.
DOI: 10.1016/j.tvjl.2015.07.011
76. Dell RB, Holleran S, Ramakrishnan R. Sample size determination. ILAR J. 2002;43(4):207-13. DOI: 10.1093/ilar.43.4.207.
DOI: 10.1093/ilar.43.4.207
77. Festing MF, Altman DG. Guidelines for the design and statistical analysis of experiments using laboratory animals. ILAR J. 2002;43(4):244-58. DOI: 10.1093/ilar.43.4.244.
DOI: 10.1093/ilar.43.4.244

Artículos relacionados

Pain trajectories and neuropathic pain symptoms following lung cancer surgery: a prospective cohort study

Rev. Soc. Esp. Dolor. 2023; 30(4): 270-283 / DOI: 10.1002/ejp.2265

Abdominopelvic neuropathic pain secondary to involvement of the anterior cutaneous, iliohypogastric, and ilioinguinal nerves: case report and review of the literature

Rev. Soc. Esp. Dolor. 2023; 30(4): 265-269 / DOI: 10.20986/resed.2024.4054/2023

Fibromyalgia, mitochondrial dysfunction, oxidative stress and inflammation: ozone as a multitarget treatment. Case report and review of literature

Rev. Soc. Esp. Dolor. 2023; 30(4): 258-264 / DOI: 10.20986/resed.2023.3987/2022

Exosomes as a potential therapeutic strategy for low back pain: literature review

Rev. Soc. Esp. Dolor. 2023; 30(4): 243-249 / DOI: 10.20986/resed.2023.4075/2023

Care needs of intrathecal infusion therapy in patients with cancer pain

Rev. Soc. Esp. Dolor. 2023; 30(4): 227-242 / DOI: 10.20986/resed.2024.4099/2023

Continuous electrical stimulation for the treatment of trigeminal neuralgia. A systematic review

Rev. Soc. Esp. Dolor. 2023; 30(4): 217-226 / DOI: 10.20986/resed.2023.4043/2022

Problems and adverse reactions related to dipyrone in Colombia

Rev. Soc. Esp. Dolor. 2023; 30(4): 210-216 / DOI: 10.20986/resed.2023.4025/2022

Editorial by the President of the Spanish Pain Society

Rev. Soc. Esp. Dolor. 2024; 31(13): 1-1

Editorial by the President of the Spanish Pain Society

Rev. Soc. Esp. Dolor. 2023; 30(14): 1-1

Abstracts

Rev. Soc. Esp. Dolor. 2023; 30(13): 3-169

Editorial by the President of the Spanish Pain Society

Rev. Soc. Esp. Dolor. 2023; 30(13): 1-1

Virtual reality increases pressure pain threshold and lowers anxiety in children compared with control and non-immersive control— randomized, crossover trial

Rev. Soc. Esp. Dolor. 2023; 30(3): 196-206

Persistent headache after craniotomy for meningioma: charting of the afferent pathways for nociception: a discussion

Rev. Soc. Esp. Dolor. 2023; 30(3): 191-195 / DOI: 10.20986/resed.2023.4069/2023

A case of neuralgic amyotrophy after vaccination against COVID-19

Rev. Soc. Esp. Dolor. 2023; 30(3): 187-190 / DOI: 10.20986/resed.2023.4021/2022

Ultrasound-guided ankle nerve block as adjuvant therapy in chronic pain after occupational injury.

Rev. Soc. Esp. Dolor. 2023; 30(3): 178-186 / DOI: 10.20986/resed.2023.4035/2022

Effectiveness of adding posterior capsule stretching after an exercise program in patients with subacromial impingement syndrome: a randomized clinical study

Rev. Soc. Esp. Dolor. 2023; 30(3): 168-177 / DOI: 10.20986/resed.2023.3927/2021

Impact on quality of life, depression and analgesic use, are associated with suffering in fibromyalgia patients. A cross-sectional study

Rev. Soc. Esp. Dolor. 2023; 30(3): 159-167 / DOI: 10.20986/resed.2023.4061/2023

A road trip to chemotherapy-induced neuropathic pain

Rev. Soc. Esp. Dolor. 2023; 30(3): 155-156 / DOI: 10.20986/resed.2023.4110/2023

Pain paths among post-COVID-19 condition subjects: a prospective cross-sectional study with in-person evaluation

Rev. Soc. Esp. Dolor. 2023; 30(2): 131-145 / DOI: 10.1002/ejp.2094

Pharmacogenetics in analgesic response: towards a sex-differences personalized medicine

Rev. Soc. Esp. Dolor. 2023; 30(2): 115-124 / DOI: 10.20986/resed.2023.4042/2022

Superior hypogastric plexus block for the management of non-oncological chronic pelvic pain: effectiveness and safety

Rev. Soc. Esp. Dolor. 2023; 30(2): 109-114 / DOI: 10.20986/resed.2023.4038/2022

Effect of therapeutic exercise in persons with sacroiliac joint dysfunction: a systematic review and meta-analysis

Rev. Soc. Esp. Dolor. 2023; 30(2): 95-108 / DOI: 10.20986/resed.2023.4034/2022

Knowledge, attitudes, and beliefs towards the disease in women with fibromyalgia. A qualitative study based on a focus group

Rev. Soc. Esp. Dolor. 2023; 30(2): 79-94 / DOI: 10.20986/resed.2023.4022/2022

Observational, prospective and multicenter study on the use of transmucosal fentanyl citrate in regular clinical practice for the control of breakthrough pain crises in cancer patients

Rev. Soc. Esp. Dolor. 2023; 30(2): 72-78 / DOI: 10.20986/resed.2023.4028/2022

Letter of reply to the article “Updates on the therapeutic approach in complex regional pain syndrome”

Rev. Soc. Esp. Dolor. 2023; 30(1): 63-64 / DOI: 10.20986/resed.2023.4049/2022

Not just low back pain: atypical manifestation of aortic aneurysm

Rev. Soc. Esp. Dolor. 2023; 30(1): 60-62 / DOI: 10.20986/resed.2022.3983/2022

Effects of transcranial direct current stimulation in pain and opioid consumption after spine surgery

Rev. Soc. Esp. Dolor. 2023; 30(1): 49-59 / DOI: 10.1002/ejp.1985

Pulsed radiofrequency of the supraescapular nerve in the treatment of painful shoulder

Rev. Soc. Esp. Dolor. 2023; 30(1): 36-48 / DOI: 10.20986/resed.2023.4046/2022

Effectiveness of cluneal nerve block for the treatment of chronic low back pain

Rev. Soc. Esp. Dolor. 2023; 30(1): 30-35 / DOI: 10.20986/resed.2023.4023/2022

Review of the remission and management of a cancer related pain population to a pain unit. What can we improve?

Rev. Soc. Esp. Dolor. 2023; 30(1): 7-14 / DOI: 10.20986/resed.2023.4010/2022

Can suicidal behaviour in chronic pain patients be prevented?

Rev. Soc. Esp. Dolor. 2023; 30(1): 5-6 / DOI: 10.20986/resed.2023.4080/2023

Noninvasive vagus nerve stimulation in trigeminal pain and trigemino-vagal system

Rev. Soc. Esp. Dolor. 2023; 30(1): 3-4 / DOI: 10.20986/resed.2023.4057/2023

Effectiveness of electroacupuncture and moxibustion in the treatment of postoperative anterior cruciate ligament graft pain with meniscal remodeling. Case study UNEVT 2022

Rev. Soc. Esp. Dolor. 2022; 29(3): 192-195 / DOI: 10.20986/resed.2022.4009/2022

Treatment of painful scars with 5 % lidocaine patch: clinical cases report

Rev. Soc. Esp. Dolor. 2022; 29(3): 187-191 / DOI: 10.20986/resed.2022.3997/2022

Long-term effectiveness of epidural steroid injections after new episodes of low back pain in older adults

Rev. Soc. Esp. Dolor. 2022; 29(3): 175-186 / DOI: 10.1002/ejp.1975

Usefulness of percutaneous basivertebral nerve thermorizotomy for the treatment of chronic low back pain. Literature review

Rev. Soc. Esp. Dolor. 2022; 29(3): 169-174 / DOI: 10.20986/resed.2022.4044/2022

Efficacy of physiotherapy on the anxiety and depression in patients with chronic pain: a systematic review

Rev. Soc. Esp. Dolor. 2022; 29(3): 157-168 / DOI: 10.20986/resed.2022.3994/2022

Psychological intervention program to promoted active coping in patients with chronic back pain

Rev. Soc. Esp. Dolor. 2022; 29(3): 149-156 / DOI: 10.20986/resed.2022.3993/2022

Single eco-guided intra-articular injection of hyaluronic acid in symptomatic coxarthrosis: retrospective study of the efficacy of two presentations

Rev. Soc. Esp. Dolor. 2022; 29(3): 140-148 / DOI: 10.20986/resed.2022.4014/2022

Can we modify the evolution of neuropathic pain through the skin?

Rev. Soc. Esp. Dolor. 2022; 29(3): 129-131 / DOI: 10.20986/resed.2022.4052/2022

Pain as a conditioned response

Rev. Soc. Esp. Dolor. 2022; 29(3): 127-128 / DOI: 10.20986/resed.2022.4051/2022

Another step forward in pain education: European Journal of Pain articles now in spanish language

Rev. Soc. Esp. Dolor. 2022; 29(3): 125-126 / DOI: 10.20986/resed.2022.4050/2022

Pain and rehabilitation in Parsonage-Tuner syndrome due to SARS-CoV-2: a case report

Rev. Soc. Esp. Dolor. 2022; 29(2): 119-123 / DOI: 10.20986/resed.2022.3940/2021

Peripheral facial palsy following glossopharyngeal block: a case report

Rev. Soc. Esp. Dolor. 2022; 29(2): 114-118 / DOI: 10.20986/resed.2022.3963/2021

The biopsychosocial nature of chronic pelvic floor pain: a narrative review

Rev. Soc. Esp. Dolor. 2022; 29(2): 97-113 / DOI: 10.20986/resed.2022.3981/2022

Myofascial pain syndrome in the female pelvic floor musculature. Narrative review of the literature

Rev. Soc. Esp. Dolor. 2022; 29(2): 88-96 / DOI: 10.20986/resed.2022.3970/2022

Effects of hydrotherapy on pain in osteoarthritis and fibromyalgia: a narrative review

Rev. Soc. Esp. Dolor. 2022; 29(2): 78-87 / DOI: 10.20986/resed.2022.3955/2021

Impact of the use of patient-controlled epidural analgesia on pain reduction during labor in a hospital in southwestern colombia

Rev. Soc. Esp. Dolor. 2022; 29(2): 71-77 / DOI: 10.20986/resed.2022.3959/2021

Cross-sectional study on factors related to chronic pain and its care, according to sex

Rev. Soc. Esp. Dolor. 2022; 29(2): 61-70 / DOI: 10.20986/resed.2022.3968/2022

Attitudes and current knowledge of the spanish pain treatment specialist regarding medical cannabis

Rev. Soc. Esp. Dolor. 2022; 29(13): 52-57 / DOI: 10.20986/resed.2022.4032/2022

Practical aspects of product selection and titration with medical cannabis for chronic pain management

Rev. Soc. Esp. Dolor. 2022; 29(13): 43-51 / DOI: 10.20986/resed.2022.4031/2022

Medical cannabis treatment in patients with visceral chronic pain

Rev. Soc. Esp. Dolor. 2022; 29(13): 32-42 / DOI: 10.20986/resed.2022.4030/2022

Is medical cannabis useful for the treatment of fibromyalgia?

Rev. Soc. Esp. Dolor. 2022; 29(13): 27-31 / DOI: 10.20986/resed.2022.4029/2022

Cannabinoids in neuropathic pain: lights and shadows

Rev. Soc. Esp. Dolor. 2022; 29(13): 20-26 / DOI: 10.20986/resed.2022.4027/2022

Medical cannabis and cancer: benefits for cancer pain and other related symptoms

Rev. Soc. Esp. Dolor. 2022; 29(13): 14-19 / DOI: 10.20986/resed.2022.4026/2022

Current evidence of medical cannabis treatment in patients with chronic pain

Rev. Soc. Esp. Dolor. 2022; 29(13): 10-13 / DOI: 10.20986/resed.2022.4024/2022

Some preclinical results of cannabinoids and pain

Rev. Soc. Esp. Dolor. 2022; 29(13): 3-9 / DOI: 10.20986/resed.2022.4033/2022

Lights and shadows of treating pain with medical cannabis

Rev. Soc. Esp. Dolor. 2022; 29(13): 1-2 / DOI: 10.20986/resed.2022.4036/2022

Bone pain management with opioid medication in a patient with Camurati-Engelmann disease: a case report

Rev. Soc. Esp. Dolor. 2022; 29(1): 51-55 / DOI: 10.20986/resed.2021.3930/2021

Complex regional pain syndrome, rehabilitation, pharmacotherapy, psychology.

Rev. Soc. Esp. Dolor. 2022; 29(1): 34-50 / DOI: 10.20986/resed.2022.3978/2022

Use of 8 % capsaicin patches for the treatment of lumbar neuropathic pain

Rev. Soc. Esp. Dolor. 2022; 29(1): 28-33 / DOI: 10.20986/resed.2022.3995/2022

Ultrasound guided interlaminar epidural steroid injection: the cumulative sum method (CUSUM) for performance evaluation

Rev. Soc. Esp. Dolor. 2022; 29(1): 21-27 / DOI: 10.20986/resed.2022.3988/2022

Evaluation of the analgesic efficacy of lumbar facet block as a function of the imaging technique used: ultrasound versus fluoroscopy

Rev. Soc. Esp. Dolor. 2022; 29(1): 15-20 / DOI: 10.20986/resed.2022.3969/2021

OFA in major surgery. Experience at a secondary level hospital

Rev. Soc. Esp. Dolor. 2022; 29(1): 8-14 / DOI: 10.20986/resed.2022.3991/2022

Spontaneous pain is very "sympathetic"

Rev. Soc. Esp. Dolor. 2022; 29(1): 4-5 / DOI: 10.20986/resed.2022.3999/2022

Complex regional pain syndrome: the challenges and opportunities of an evolving disease

Rev. Soc. Esp. Dolor. 2022; 29(1): 1-3 / DOI: 10.20986/resed.2022.3998/2022

Peroneal neuropathy caused by an extraneural ganglion: literary review and treatment proposal. A non-positive case

Rev. Soc. Esp. Dolor. 2021; 28(6): 354-357 / DOI: 10.20986/resed.2022.3919/2021

Retrolaminar ultrasound guided block as analgesic treatment for post herpetic neuralgia: case report

Rev. Soc. Esp. Dolor. 2021; 28(6): 350-353 / DOI: 10.20986/resed.2022.3920/2021

Recommendations for the safe prescription of opioids in patients with a history or risk of abuse

Rev. Soc. Esp. Dolor. 2021; 28(6): 343-349 / DOI: 10.20986/resed.2022.3935/2021

Use of botulinum toxin for pain after amputation

Rev. Soc. Esp. Dolor. 2021; 28(6): 332-342 / DOI: 10.20986/resed.2022.3943/2021

Lumbar epidural steroids injections reduce catastrophism on the lumbosacral radicular syndrome

Rev. Soc. Esp. Dolor. 2021; 28(6): 325-331 / DOI: 10.20986/resed.2022.3947/2021

End-of-life transfusions in patients with an oncological diagnosis

Rev. Soc. Esp. Dolor. 2021; 28(6): 319-324 / DOI: 10.20986/resed.2022.3956/2021

Preliminary study on the evaluation of mechanical pressure pain and central pain modulation mechanisms by algometry in an anesthesia unit

Rev. Soc. Esp. Dolor. 2021; 28(6): 311-318 / DOI: 10.20986/resed.2022.3885/2021

Is pulsed radiofrequency worthwhile compared to ablative techniques in gonalgia secondary to osteoarthritis: what do we think?

Rev. Soc. Esp. Dolor. 2021; 28(6): 309-310 / DOI: 10.20986/resed.2022.3977/2022

New opioids with different intracellular mechanism of action; is a new therapeutic window opening up?

Rev. Soc. Esp. Dolor. 2021; 28(5): 292-297 / DOI: 10.20986/resed.2021.3891/2021

A new paradigm for the treatment of knee osteoarthritis: the role of hyaluronic acid, platelet-rich plasma (PRP) and ozone in the modulation of inflammation: a review

Rev. Soc. Esp. Dolor. 2021; 28(5): 282-291 / DOI: 10.20986/resed.2021.3903/2021

Thalalgic triad. A new clinical entity from a case series

Rev. Soc. Esp. Dolor. 2021; 28(5): 276-281 / DOI: 10.20986/resed.2021.3941/2021

Efficacy and complications of analgesic techniques for the treatment of moderate to severe postoperative acute pain

Rev. Soc. Esp. Dolor. 2021; 28(5): 264-265 / DOI: 10.20986/resed.2021.3942/2021

Descriptive study on the profile of patients sent to the Chronic Pain Treatment Unit of the University Hospital of Gran Canaria Dr. Negrín (UTDC-HUGCDN) as a basis for the reorganization of this

Rev. Soc. Esp. Dolor. 2021; 28(5): 254-263 / DOI: 10.20986/resed.2021.3939/2021

Myalgic encephalitis or chronic fatigue syndrome, implications in its approach in pain units in the post-COVID era

Rev. Soc. Esp. Dolor. 2021; 28(5): 250-251 / DOI: 10.20986/resed.2021.3960/2021

Pain, emotions and locus coeruleus

Rev. Soc. Esp. Dolor. 2021; 28(5): 247-249 / DOI: 10.20986/resed.2021.3965/2021

Treatment by ultrasound-guided neurolysis with 6 % aqueous phenol of the pain component for post-amputation neuromas: report of a clinical case

Rev. Soc. Esp. Dolor. 2021; 28(4): 239-241 / DOI: 10.20986/resed.2021.3928/2021

The unsolved problem of postoperative pain: critical analysis and prospects for improvement

Rev. Soc. Esp. Dolor. 2021; 28(4): 232-238 / DOI: 10.20986/resed.2021.3917/2021

Dorsal root ganlion pulsed radiofrequency for lumbosacral radicular pain: a narrative review

Rev. Soc. Esp. Dolor. 2021; 28(4): 219-231 / DOI: 10.20986/resed.2021.3882/2021

Clinical recommendations for rehabilitation of people with fibromyalgia. A narrative review

Rev. Soc. Esp. Dolor. 2021; 28(4): 194-210 / DOI: 10.20986/resed.2021.3932/2021

Psychological factors associated with the adherence to analgesic treatment in patients with chronic pain: systematic review of the literature

Rev. Soc. Esp. Dolor. 2021; 28(4): 181-193 / DOI: 10.20986/resed.2021.3922/2021

Comment to the article “radiofrequency intraosseous ablation of the vertebral basicervical nerve. Solution in refractory discogenic pain?”

Rev. Soc. Esp. Dolor. 2021; 28(2): 172-173 / DOI: 10.20986/resed.2021.3929/2021

Persistent hiccups after epidural injection of betamethasone: a case report

Rev. Soc. Esp. Dolor. 2021; 28(2): 169-171 / DOI: 10.20986/resed.2021.3914/2021

Genicular nerve radiofrequency in osteoarthritis-related chronic knee pain

Rev. Soc. Esp. Dolor. 2021; 28(3): 154-168 / DOI: 10.20986/resed.2021.3900/2021

Observational and prospective study on the effectiveness and safety of the dorsal root ganglion stimulation in patients with refractory neuropathic pain

Rev. Soc. Esp. Dolor. 2021; 28(2): 148-156 / DOI: 10.20986/resed.2021.3879/2020

Prescribing habits for neuropathic pain management in Spain: results of the survey of the neuropathic pain working group of the Spanish Pain Society

Rev. Soc. Esp. Dolor. 2021; 28(3): 137-147 / DOI: 10.20986/resed.2021.3911/2021

Epidemiological profile of pain secondary to moderate diabetic peripheral neuropathy

Rev. Soc. Esp. Dolor. 2021; 28(2): 129-136 / DOI: 10.20986/resed.2021.3826/2020

Results of an interdisciplinary psychoeducational intervention with EMDR in patients with fibromyalgia: a private center experience

Rev. Soc. Esp. Dolor. 2021; 28(2): 119-128 / DOI: 10.20986/resed.2021.3897/2021

Transcutaneous electrical nerve stimulation (TENS) as effective pain and fatigue management in women with fibromyalgia

Rev. Soc. Esp. Dolor. 2021; 28(2): 117-118 / DOI: 10.20986/resed.2021.3931/2021

Does it decrease the efficacy or safety of COVID-19 vaccines in patients with chronic pain?

Rev. Soc. Esp. Dolor. 2021; 28(2): 115-116 / DOI: 10.20986/resed.2021.3933/2021

Neuropathic pain: a constant challenge

Rev. Soc. Esp. Dolor. 2021; 28(2): 111-114 / DOI: 10.20986/resed.2021.3938/2021

Botulinum toxin for the treatment of myofascial pain syndrome

Rev. Soc. Esp. Dolor. 2021; 28(2): 100-110 / DOI: 10.20986/resed.2021.3902/2021

Postoperative ketamine efficacy in patients receiving chronic opioids undergoing spinal surgery

Rev. Soc. Esp. Dolor. 2021; 28(2): 92-99 / DOI: 10.20986/resed.2021.3825/2020

Risk of misuse of prescribed opioids in patients with chronic noncancer pain in a workers compensation system hospital in Chile

Rev. Soc. Esp. Dolor. 2021; 28(2): 82-91 / DOI: 10.20986/resed.2021.3845/2020

Evolution of low back pain in cancer patients treated with interventional pain management

Rev. Soc. Esp. Dolor. 2021; 28(2): 76-81 / DOI: 10.20986/resed.2021.3901/2021

Analgesic effectiveness of tapentadol in neuropathic pain secondary to post-laminectomy syndrome

Rev. Soc. Esp. Dolor. 2021; 28(2): 71-75 / DOI: 10.20986/resed.2021.3822/2020

Radiofrequency intraosseous ablation of the vertebral basicervical nerve. Solution in refractory discogenic pain?

Rev. Soc. Esp. Dolor. 2021; 28(2): 69-70 / DOI: 10.20986/resed.2021.3926/2021

Usefulness or necessity of ketamine in postoperative pain

Rev. Soc. Esp. Dolor. 2021; 28(2): 63-66 / DOI: 10.20986/resed.2021.3921/2021

Parsonage-turner after rabies vaccination due to bat bite: case report

Rev. Soc. Esp. Dolor. 2021; 28(1): 57-61 / DOI: 10.20986/resed.2021.3832/2020

Bilateral spinal erector plane block for pectus excavatum surgery in pediatric patient

Rev. Soc. Esp. Dolor. 2021; 28(1): 53-56 / DOI: 10.20986/resed.2021.3846/2020

Inflammatory mediators: its connection with chronic pain and associated problems. Review

Rev. Soc. Esp. Dolor. 2021; 28(1): 37-46 / DOI: 10.20986/resed.2021.3841/2020

Management and perception of therapeutic adherence of breakthrough cancer pain by oncologists in Spain

Rev. Soc. Esp. Dolor. 2021; 28(1): 19-26 / DOI: 10.20986/resed.2021.3824/2020

Implementation and evaluation of a multimodal analgesia protocol for total knee arthroplasty including ultrasoundguided adductor canal block and periarticular local anesthetic infiltration

Rev. Soc. Esp. Dolor. 2021; 28(1): 9-18 / DOI: 10.20986/resed.2021.3847/2020

Pain related to oncologic process: old concepts and new horizons

Rev. Soc. Esp. Dolor. 2021; 28(1): 1-4 / DOI: 10.20986/resed.2021.3905/2021

Interventional management of osteoarthritic pain

Rev. Soc. Esp. Dolor. 2021; 28(13): 85-90 / DOI: 10.20986/resed.2021.3853/2020

Platelet rich plasma and intra-articular mesenchymal stem cells in osteoarthritis

Rev. Soc. Esp. Dolor. 2021; 28(13): 80-84 / DOI: 10.20986/resed.2021.3858/2020

Intra-articular botulinum toxin and ozone in osteoarthritis

Rev. Soc. Esp. Dolor. 2021; 28(13): 73-79 / DOI: 10.20986/resed.2021.3857/2020

Infiltrations of steroids and hyaluronic acid in osteoarthritis

Rev. Soc. Esp. Dolor. 2021; 28(13): 64-72 / DOI: 10.20986/resed.2021.3854/2020

New pharmacological targets for osteoarthritis induced pain

Rev. Soc. Esp. Dolor. 2021; 28(13): 57-63 / DOI: 10.20986/resed.2021.3863/2020

Opioids in osteoarthritis

Rev. Soc. Esp. Dolor. 2021; 28(13): 49-56 / DOI: 10.20986/resed.2021.3855/2020

Review of the pharmacological treatment of osteoarthritis pain with paracetamol, non-steroid anti-inflammatory (NSAIDSS) and selective cyclooxygenase-2 inhibitors (COXIB)

Rev. Soc. Esp. Dolor. 2021; 28(13): 43-48 / DOI: 10.20986/resed.2021.3864/2020

News in the clinical practice guidelines regarding the treatment of the hip, knee and hands osteoarthritis

Rev. Soc. Esp. Dolor. 2021; 28(13): 38-42 / DOI: 10.20986/resed.2021.3870/2020

Central sensitization in osteoarthritis

Rev. Soc. Esp. Dolor. 2021; 28(13): 31-37 / DOI: 10.20986/resed.2021.3876/2020

Ethiopathogenic mechanism of osteoarthritis

Rev. Soc. Esp. Dolor. 2021; 28(13): 11-17 / DOI: 10.20986/resed.2021.3851/2020

Epidemiology, clinical impact and therapeutic objectives in osteoarthritis

Rev. Soc. Esp. Dolor. 2021; 28(13): 4-10 / DOI: 10.20986/resed.2021.3874/2020

Osteoarthritis and pain: the complexity and impact of a symptom

Rev. Soc. Esp. Dolor. 2021; 28(13): 1-3 / DOI: 10.20986/resed.2021.3886/2021

Adaptation of the chronic pain unit of the Hospital Complex from Vigo to the state of alarm due to the SARS-CoV-2 pandemic

Rev. Soc. Esp. Dolor. 2020; 27(6): 392-393 / DOI: 10.20986/resed.2020.3827/2020

Effectiveness and current recommendation of manual therapy on hip osteoarthritis. An overview

Rev. Soc. Esp. Dolor. 2020; 27(6): 375-391 / DOI: 10.20986/resed.2021.3835/2020

Transitional pain clinic

Rev. Soc. Esp. Dolor. 2020; 27(6): 369-374 / DOI: 10.20986/resed.2020.3840/2020

Study of pain in rehabilitation treatments

Rev. Soc. Esp. Dolor. 2020; 27(6): 361-368 / DOI: 10.20986/resed.2020.3809/2020

Impact of group psychological intervention on conventional radiofrequency tributary patients

Rev. Soc. Esp. Dolor. 2020; 27(6): 349-360 / DOI: 10.20986/resed.2020.3830/2020

Calcific tendinitis of the shoulder: risk factors and effectiveness of iontophoresis with acetic acid 5 % plus ultrasound: prospective quasi-experimental study at 5 years with 138 cases

Rev. Soc. Esp. Dolor. 2020; 27(6): 340-348 / DOI: 10.20986/resed.2020.3842/2020

Physical medicine, rehabilitation and pain

Rev. Soc. Esp. Dolor. 2020; 27(6): 333-335 / DOI: 10.20986/resed.2021.3888/2021

A 14-month physiotherapy follow up to a child with Sandifer syndrome

Rev. Soc. Esp. Dolor. 2020; 27(5): 329-331 / DOI: 10.20986/resed.2020.3816/2020

School of non-oncologic chronic pain patients and opioid treatment

Rev. Soc. Esp. Dolor. 2020; 27(5): 324-328 / DOI: 10.20986/resed.2020.3804/2020

Opioid misuse in patients with cancer pain: an integrative systematic review of the literature

Rev. Soc. Esp. Dolor. 2020; 27(5): 306-315 / DOI: 10.20986/resed.2020.3801/2020

Therapeutic failure of the lumbar medial branch block and its relation to obesity. Retrospective cohort study

Rev. Soc. Esp. Dolor. 2020; 27(5): 298-305 / DOI: 10.20986/resed.2020.3829/2020

Identification of signs and symptoms for the diagnosis of discogenic low back pain: mapping review

Rev. Soc. Esp. Dolor. 2020; 27(5): 292-297 / DOI: 10.20986/resed.2020.3803/2020

Efficacy of lidocaine perfusions in fibromyalgia: a prospective cohort study

Rev. Soc. Esp. Dolor. 2020; 27(5): 287-291 / DOI: 10.20986/resed.2020.3796/2020

Back to the future in the treatment of postoperative acute pain

Rev. Soc. Esp. Dolor. 2020; 27(5): 285-286 / DOI: 10.20986/resed.2020.3850/2020

Temporary peripheral nerve stimulation in cancer pain: opportunity options

Rev. Soc. Esp. Dolor. 2020; 27(5): 283-284 / DOI: 10.20986/resed.2020.3849/2020

Facings with discogenic pain

Rev. Soc. Esp. Dolor. 2020; 27(5): 281-282 / DOI: 10.20986/resed.2020.3848/2020

Pain: a "hotchpotch"

Rev. Soc. Esp. Dolor. 2020; 27(4): 278-280 / DOI: 10.20986/resed.2016.3507/2016

Splanchnic nerve block for the treatment of benign chronic abdominal pain. a case report and literature review

Rev. Soc. Esp. Dolor. 2020; 27(4): 273-277 / DOI: 10.20986/resed.2020.3818/2020

Continuous analgesic control in a patient with multiple rib fractures by placing a catheter in the deep plane of the erector muscle of the spine

Rev. Soc. Esp. Dolor. 2020; 27(4): 269-272 / DOI: 10.20986/resed.2020.3800/2020

Clinical pathophysiology in patients with sickle cell disease: the transition from acute to chronic pain

Rev. Soc. Esp. Dolor. 2020; 27(4): 257-268 / DOI: 10.20986/resed.2020.3814/2020

Gender determinants in the approach to chronic pain

Rev. Soc. Esp. Dolor. 2020; 27(4): 252-256 / DOI: 10.20986/resed.2020.3802/2020

Incidence of postmastectomy pain syndrome. Retrospective analysis

Rev. Soc. Esp. Dolor. 2020; 27(4): 246-251 / DOI: 10.20986/resed.2020.3797/2020

Sociodemographic and clinical characterization in patients with chronic back pain, Cienfuegos 2019

Rev. Soc. Esp. Dolor. 2020; 27(4): 239-245 / DOI: 10.20986/resed.2020.3798/2020

Spinal cord stimulation. Analysis of the diagnostic indications

Rev. Soc. Esp. Dolor. 2020; 27(4): 234-238 / DOI: 10.20986/resed.2020.3777/2019

Updated version of the IASP definition of pain: one step forward or one step back

Rev. Soc. Esp. Dolor. 2020; 27(4): 232-233 / DOI: 10.20986/resed.2020.3839/2020

Metamizole as an immunomodulator in neuropathic pain

Rev. Soc. Esp. Dolor. 2020; 27(4): 230-231 / DOI: 10.20986/resed.2020.3838/2020

Suboccipital decompression as an alternative in the treatment of pain secundary to occipital neuralgia: a case series

Rev. Soc. Esp. Dolor. 2020; 27(3): 221-226 / DOI: 10.20986/resed.2020.3791/2020

Analgesic effect of the capsaicin 8 % patch through the TRPV-1 receptor in a case of parkinson desease with located neuropathic pain

Rev. Soc. Esp. Dolor. 2020; 27(3): 216-22 / DOI: 10.20986/resed.2020.3786/2019

Spanish Pain Society (SPS). Healthcare recommendations for pain units in the face of progressive normalization of activity during the COVID-19 pandemic

Rev. Soc. Esp. Dolor. 2020; 27(3): 192-215 / DOI: 10.20986/resed.2020.3821/2020

Symptomatic treatment for migraña. Drugs used and related variables. Results of the european survey on work and migraine

Rev. Soc. Esp. Dolor. 2020; 27(3): 178-191 / DOI: 10.20986/resed.2020.3744/2019

Characteristics of patients suffering mild to severe pain treated with orodispersible tablets of paracetamol 325 mg/tramadol HCL 37,5mg (Paxiflas®) in comparison with other oral formulations containing the same combination. PROPAX study

Rev. Soc. Esp. Dolor. 2020; 27(3): 168-177 / DOI: 10.20986/resed.2020.3771/2019

Biomechanical factors related to surgical outcomes on patients treated with lumbar arthrodesis in a high complexity center in Colombia

Rev. Soc. Esp. Dolor. 2020; 27(3): 160-167 / DOI: 10.20986/resed.2020.3759/2019

Drug consumption used for musculoskeletal pain treatment in a cohort of blue-collar workers in Zaragoza (Spain)

Rev. Soc. Esp. Dolor. 2020; 27(3): 150-159 / DOI: 10.20986/resed.2020.3749/2019

The pandemic that surprised us and has altered the care of patients with pain

Rev. Soc. Esp. Dolor. 2020; 27(3): 148-149 / DOI: 10.20986/resed.2020.3820/2020

The Pain Units in the COVID-19 era

Rev. Soc. Esp. Dolor. 2020; 27(3): 143-145 / DOI: 10.20986/resed.2020.3823/2020

Erector spinalis plane block as a neuropathic pain management in post-burned pediatric patient

Rev. Soc. Esp. Dolor. 2020; 27(2): 127-132 / DOI: 10.20986/resed.2020.3776/2019

Management of breakthrough pain associated with the cure of skin ulcers

Rev. Soc. Esp. Dolor. 2020; 27(2): 113-126 / DOI: 10.20986/resed.2020.3755/2019

Efficacy of a preincisional analgesic strategy with ibuprofen, paracetamol and dexamethasone in laparoscopic cholecystectomy. Prospective observational study

Rev. Soc. Esp. Dolor. 2020; 27(2): 104-112 / DOI: 10.20986/resed.2020.3778/2019

E-consults, a new tool for pain management. Results of its implementation in an organizational structure of integrated management (EOXI)

Rev. Soc. Esp. Dolor. 2020; 27(2): 97-103 / DOI: 10.20986/resed.2020.3756/2019

Ethical problems in the management of pain. Qualitative study through open reflection interview

Rev. Soc. Esp. Dolor. 2020; 27(2): 89-96 / DOI: 10.20986/resed.2020.3729/2019

Intra-articular ozone modulates inflammation, ameliorates pain and stiffness, improves function and has anabolic effect on knee osteoarthritis: a prospective quasiexperimental before-and-after study, 115 patients

Rev. Soc. Esp. Dolor. 2020; 27(2): 78-88 / DOI: 10.20986/resed.2020.3775/2019

Altruistic conduct: a behavioral strategy to decrease the perception of pain?

Rev. Soc. Esp. Dolor. 2020; 27(2): 76-77 / DOI: 10.20986/resed.2020.3806/2020

COVID-19 coronavirus and chronic pain: uncertainties

Rev. Soc. Esp. Dolor. 2020; 27(2): 72-73 / DOI: 10.20986/resed.2020.3808/2020

The ozone paradigm in pain treatment

Rev. Soc. Esp. Dolor. 2020; 27(2): 69-71 / DOI: 10.20986/resed.2020.3807/2020

Conventional radiofrequency for genicular nerves in treatment of knee osteoarthritis

Rev. Soc. Esp. Dolor. 2020; 27(1): 59-60 / DOI: 10.20986/resed.2016.3515/2016

Review of the impact of acupuncture treatment on the management of nonspecific low back pain

Rev. Soc. Esp. Dolor. 2020; 27(1): 53-58 / DOI: 10.20986/resed.2020.3762/2019

Effectiveness of the association of lacosamide in trigeminal neuralgia

Rev. Soc. Esp. Dolor. 2020; 27(1): 50-52 / DOI: 10.20986/resed.2019.3738/2019

Peripheral acting Mu opioid receptor antagonists in the treatment of the opioid-induced constipation: review

Rev. Soc. Esp. Dolor. 2020; 27(1): 37-49 / DOI: 10.20986/resed.2020.3717/2018

Effectiveness of patient-controlled analgesia in acute and chronic pain after cardiac surgery: a prospective study

Rev. Soc. Esp. Dolor. 2020; 27(1): 24-36 / DOI: 10.20986/resed.2020.3747/2019

Efficacy of pregabalin, gabapentin and duloxetine in neuropathic pain verified by the p-curve analysis

Rev. Soc. Esp. Dolor. 2020; 27(1): 16-23 / DOI: 10.20986/resed.2020.3727/2019

Quasi-experimental study on effectiveness of music therapy to reduce anxiety before an interventional technique in the pain unit

Rev. Soc. Esp. Dolor. 2020; 27(1): 7-15 / DOI: 10.20986/resed.2020.3767/2019

Spinal stimulation modulated automatically. Evidence of closed stimulation systems: towards the pain pacemaker

Rev. Soc. Esp. Dolor. 2020; 27(1): 5-6 / DOI: 10.20986/resed.2020.3793/2020

News in the treatment of back pain: are the future cell therapies?

Rev. Soc. Esp. Dolor. 2020; 27(1): 3-4 / DOI: 10.20986/resed.2020.3792/2020

Considerations for the use of evidence-based practice in the management of people with pain

Rev. Soc. Esp. Dolor. 2019; 26(6): 374-375 / DOI: 10.20986/resed.2019.3712/2018

Intratecal baclophene for the treatment of pain and spasticity in stiff man syndrome: a case report

Rev. Soc. Esp. Dolor. 2019; 26(6): 368-371 / DOI: 10.20986/resed.2019.3745/2019

Key factors governing spinal cord opioid bioavailability in the management of acute pain

Rev. Soc. Esp. Dolor. 2019; 26(6): 359-367 / DOI: 10.20986/resed.2019.3737/2019

Neurolytic procedures for pancreatic cáncer pain: a systematic review and a proposal for an algorithm treatment

Rev. Soc. Esp. Dolor. 2019; 26(6): 342-358 / DOI: 10.20986/resed.2019.3715/2018

Valuation of the relationship between the rotational restriction of high cervical column and high thoracic column in students with and without cervical pain of the Faculty of Sciences of the Rehabilitation

Rev. Soc. Esp. Dolor. 2019; 26(6): 337-341 / DOI: 10.20986/resed.2019.3698/2018

Correlation study between diagnostic opportunity and pain severity in patients with fibromyalgia who enter the Nononcological Chronic Pain Unit at the San Borja Arriarán Clinical Hospital

Rev. Soc. Esp. Dolor. 2019; 26(6): 331-336 / DOI: 10.20986/resed.2019.3690/2018

Correlation between pain and radiological parameters in patients older than 60 years of age with distal radius fracture

Rev. Soc. Esp. Dolor. 2019; 26(6): 324-330 / DOI: 10.20986/resed.2019.3720/2018

Connexins in chronic pain. A new target?

Rev. Soc. Esp. Dolor. 2019; 26(6): 322-323 / DOI: 10.20986/resed.2019.3785/2019

Celiac axis block in cancer pain: medicine of opportunity

Rev. Soc. Esp. Dolor. 2019; 26(6): 317-319 / DOI: 10.20986/resed.2019.3787/2019

Pyoderma gangrenosum, undocumented complication of a spinal cord stimulation

Rev. Soc. Esp. Dolor. 2019; 26(5): 309-312 / DOI: 10.20986/resed.2019.3725/2019

Applicability of scales/indicators for pain monitoring in critically ill patients incapable of verbalizing: a systematic review of the literature

Rev. Soc. Esp. Dolor. 2019; 26(5): 293-303 / DOI: 10.20986/resed.2019.3726/2019

The medical doctors who perform their care and research work in pain units in the use of the internet: identification, characterization and determinants

Rev. Soc. Esp. Dolor. 2019; 26(5): 284-292 / DOI: 10.20986/resed.2019.3713/2018

Validation of the coping strategies to chronic pain reduced questionnaire in the cienfuegan population with chronic back pain (2017-2018)

Rev. Soc. Esp. Dolor. 2019; 26(5): 276-283 / DOI: 10.20986/resed.2019.3732/2019

New strategies for postoperative pain control in tonsillectomy surgery. Is all that glitters gold?

Rev. Soc. Esp. Dolor. 2019; 26(5): 270-275 / DOI: 10.20986/resed.2019.3742/2019

Epidural betamethasone injection in lumbosacral radicular syndrome: effi cacy evaluation for interlaminar and transforaminal approaches

Rev. Soc. Esp. Dolor. 2019; 26(5): 263-269 / DOI: 10.20986/resed.2019.3700/2018

The use of new technologies in patients with chronic pain. A reality that cannot be denied

Rev. Soc. Esp. Dolor. 2019; 26(5): 259-260 / DOI: 10.20986/resed.2019.3766/2019

Epidural injections: caudal, interlaminar or transforaminal. More than a shot

Rev. Soc. Esp. Dolor. 2019; 26(5): 255-258 / DOI: 10.20986/resed.2019.3764/2019

New ACP guidelines for non-radicular low back pain

Rev. Soc. Esp. Dolor. 2019; 26(4): 254-254 / DOI: 10.20986/resed.2017.3590/2017

Painful diabetic foot ulcer amputation avoided thanks to topical sevoflurane

Rev. Soc. Esp. Dolor. 2019; 26(4): 253-253 / DOI: 10.20986/resed.2018.3683/2018

Open-label, prospective, safety, tolerability and sensory function study after of capsaicin 8 % patch repeat treatment in non-diabetic peripheral neuropathic pain: stride study

Rev. Soc. Esp. Dolor. 2019; 26(4): 251-252 / DOI: 10.20986/resed.2017.3564/2017

NMDA antagonism in the treatment of cluster headache

Rev. Soc. Esp. Dolor. 2019; 26(4): 247-250 / DOI: 10.20986/resed.2019.3710/2018

Orofacial pain in the dental clinic

Rev. Soc. Esp. Dolor. 2019; 26(4): 233-242 / DOI: 10.20986/resed.2019.3724/2019

Role of depressive symptomatology, catastrophism and expectation in the efficacy of interventional treatment in chronic low back pain

Rev. Soc. Esp. Dolor. 2019; 26(4): 227-232 / DOI: 10.20986/resed.2019.3704/2018

Characterization of pain in patients with breast cancer attending the Oncology Unit of the San José Hospital

Rev. Soc. Esp. Dolor. 2019; 26(4): 221-226 / DOI: 10.20986/resed.2019.3692/2018

Comparative analysis of vital signs in acutely hospitalized patients according to the pain intensity

Rev. Soc. Esp. Dolor. 2019; 26(4): 215-220 / DOI: 10.20986/resed.2019.3707/2018

The new international classification of diseases (ICD-11) and chronic pain. Pragmatical implications

Rev. Soc. Esp. Dolor. 2019; 26(4): 209-210 / DOI: 10.20986/resed.2019.3752/2019

Manual therapy, a double-edged weapon in the management of chronic pain

Rev. Soc. Esp. Dolor. 2019; 26(3): 206-207 / DOI: 10.20986/resed.2018.3675/2018

Opioid tapering may improve outcomes for chronic pain patients

Rev. Soc. Esp. Dolor. 2019; 26(3): 204-205 / DOI: 10.20986/resed.2017.3615/2017

Body pain, ethics and empathy: Utopia in the time of the mediate?

Rev. Soc. Esp. Dolor. 2019; 26(3): 203-203 / DOI: 10.20986/resed.2017.3599/2017

Erector spinae plane block for multiple unilateral ribs fractures.

Rev. Soc. Esp. Dolor. 2019; 26(3): 199-202 / DOI: 10.20986/resed.2019.3687/2018

Pain in Parkinson's disease. A look at a little known aspect of this pathology

Rev. Soc. Esp. Dolor. 2019; 26(3): 184-198 / DOI: 10.20986/resed.2019.3733/2019

Information and communication technologies applied among medical professionals who perform pain treatment

Rev. Soc. Esp. Dolor. 2019; 26(3): 175-183 / DOI: 10.20986/resed.2019.3709/2018

Pulsed radiofrequency of the dorsal root ganglion for chronic lumbosacral radicular syndrome refractory to epidural steroid injections

Rev. Soc. Esp. Dolor. 2019; 26(3): 166-174 / DOI: 10.20986/resed.2019.3702/2018

Optimization of postoperative pain management based on a new technological tool. Pain map

Rev. Soc. Esp. Dolor. 2019; 26(3): 154-165 / DOI: 10.20986/resed.2019.3696/2018

Sublingual fentanyl for the treatment of breakthrough cancer pain during allergic reactions to chemotherapy infusion

Rev. Soc. Esp. Dolor. 2019; 26(3): 148-153 / DOI: 10.20986/resed.2018.3689/2018

Recent advances in the use of light in pain research. Implications in physiology and pharmacology

Rev. Soc. Esp. Dolor. 2019; 26(3): 146-147 / DOI: 10.20986/resed.2019.3743/2019

Evidence and foresight of ultrasound-guided blocks for the painful shoulder

Rev. Soc. Esp. Dolor. 2019; 26(3): 144-145 / DOI: 10.20986/resed.2019.3741/2019

Situation of acute postoperative pain in the Spanish National Health System. Icts help to reach a “pain-free” hospital an primary care

Rev. Soc. Esp. Dolor. 2019; 26(3): 139-143 / DOI: 10.20986/resed.2019.3739/2019

Explanations on the article “Recommendations based on evidence for the management of neuropathic pain (review of the literature)”

Rev. Soc. Esp. Dolor. 2019; 26(2): 134-137 / DOI: 10.20986/resed.2019.3723/2019

Main pharmacodynamic differences and receptor affinities between serotonin-norepinephrine reuptake inhibitors: clinical implications in the management of neuropathic pain

Rev. Soc. Esp. Dolor. 2019; 26(2): 131-133 / DOI: 10.20986/resed.2017.3597/2017

Top 10 bioethical issues in pain

Rev. Soc. Esp. Dolor. 2019; 26(2): 130-130 / DOI: 10.20986/resed.2018.3694/2018

Pulsed radiofrequency treatment in the neuropathy of the pudendal nerve: report of a case

Rev. Soc. Esp. Dolor. 2019; 26(2): 128-129 / DOI: 10.20986/resed.2016.3517/2016

Does pregabalin is a safe drug? Heart failure associated with pregabalin

Rev. Soc. Esp. Dolor. 2019; 26(2): 124-125 / DOI: 10.20986/resed.2017.3537/2016

Motor block after caudal epidural infiltration: a case report

Rev. Soc. Esp. Dolor. 2019; 26(2): 120-123 / DOI: 10.20986/resed.2018.3669/2018

Myofascial pain syndrome as a cause of postoperative acute pain in hip surgery

Rev. Soc. Esp. Dolor. 2019; 26(2): 117-119 / DOI: 10.20986/resed.2019.3655/2018

Fast opioid detoxification

Rev. Soc. Esp. Dolor. 2019; 26(2): 95-102 / DOI: 10.20986/resed.2019.3681/2018

Dry needling and changes in muscular activity in subjects with myphastial trigger points: case series

Rev. Soc. Esp. Dolor. 2019; 26(2): 89-94 / DOI: 10.20986/resed.2018.3677/2018

Effectiveness of hand crossing to produce analgesia in patients with chronic pain of the upper limb

Rev. Soc. Esp. Dolor. 2019; 26(2): 81-88 / DOI: 10.20986/resed.2019.3674/2018

Profiles of personality and resilience in chronic pain: utility of the CDRISC-10 to discriminate between resilient and vulnerable types

Rev. Soc. Esp. Dolor. 2019; 26(2): 72-80 / DOI: 10.20986/resed.2018.3670/2018

Epidural steroids in lumbar radicular pain: particulate vs. non-particulate. This is the question

Rev. Soc. Esp. Dolor. 2019; 26(2): 70-71 / DOI: 10.20986/resed.2019.3735/2019

Opioids and addiction in chronic pain: is it a problem?, how to address it?

Rev. Soc. Esp. Dolor. 2019; 26(2): 65-67 / DOI: 10.20986/resed.2019.3736/2019

New indication of capsaicin 8 % patch: painful diabetic peripheral neuropathy

Rev. Soc. Esp. Dolor. 2019; 26(1): 60-61 / DOI: 10.20986/resed.2017.3556/2016

Oxytocin and chronic pain in humans

Rev. Soc. Esp. Dolor. 2019; 26(1): 52-58 / DOI: 10.20986/resed.2018.3664/2018

Influence of psychosocial factors in the experience of musculoskeletal pain: a literatura review

Rev. Soc. Esp. Dolor. 2019; 26(1): 44-51 / DOI: 10.20986/resed.2018.3679/2018

Project adapta: adequacy of treatment in breakthrough cancer pain

Rev. Soc. Esp. Dolor. 2019; 26(1): 31-43 / DOI: 10.20986/resed.2018.3661/2018

Psychosocial factors in chronic cancer pain: a Delphi study

Rev. Soc. Esp. Dolor. 2019; 26(1): 21-30 / DOI: 10.20986/resed.2018.3658/2018

Dexmedetomidine versus endovenous lidocaine in breakthrough pain control and functionality in patients with lumbar stenosis

Rev. Soc. Esp. Dolor. 2019; 26(1): 14-20 / DOI: 10.20986/resed.2018.3656/2018

Effects of multimodal treatment in patients with complex regional pain syndrome type 1 with, at least, 6 months of evolution: a descriptive study

Rev. Soc. Esp. Dolor. 2019; 26(1): 6-13 / DOI: 10.20986/resed.2018.3651/2018

Micro RNAs: A new way for the management of neuropathic pain?

Rev. Soc. Esp. Dolor. 2019; 26(1): 2-3 / DOI: 10.20986/resed.2019.3730/2019

Academic University training program of the Spanish Pain Society

Rev. Soc. Esp. Dolor. 2018; 25(6): 368-368

ACNES as a cause of chronic abdominal pain

Rev. Soc. Esp. Dolor. 2018; 25(6): 360-361 / DOI: 10.20986/resed.2017.3530/2016

Dysphonia as side-effect dose-dependent during treatment with duloxetine

Rev. Soc. Esp. Dolor. 2018; 25(6): 359-359 / DOI: 10.20986/resed.2017.3528/2016

Evidence-based recommendations for the management of neuropathic pain (review of the literature)

Rev. Soc. Esp. Dolor. 2018; 25(6): 349-358 / DOI: 10.20986/resed.2018.3673/2018

Changes in intraocular pressure in patients with trigeminal neuralgia subject to radio frequency of the Gasserian ganglion

Rev. Soc. Esp. Dolor. 2018; 25(6): 342-348 / DOI: 10.20986/resed.2018.3657/2018

Nerve distribution in human temporomandibular articular disc using Sihler staining technique: a cadaveric descriptive approach

Rev. Soc. Esp. Dolor. 2018; 25(6): 335-341 / DOI: 10.20986/resed.2018.3646/2017

Opinaudit study: clinical uses in breakthrough pain, is scientific evidence being followed up?

Rev. Soc. Esp. Dolor. 2018; 25(6): 325-334 / DOI: 10.20986/resed.2018.3634/2017

Use of major opioids for control of pain in hospitalized patients

Rev. Soc. Esp. Dolor. 2018; 25(6): 318-324 / DOI: 10.20986/resed.2018.3629/2017

Proctalgia and pudendal nerve entrapment: an association to know

Rev. Soc. Esp. Dolor. 2018; 25(6): 311-317 / DOI: 10.20986/resed.2018.3623/2017

Consensus for the definition of post-mastectomy pain syndrome

Rev. Soc. Esp. Dolor. 2018; 25(5): 305-306 / DOI: 10.20986/resed.2016.3510/2016

Radiofrequency thermal and splanchnics nerves block

Rev. Soc. Esp. Dolor. 2018; 25(5): 303-304 / DOI: 10.20986/resed.2016.3509/2016

Implications of bioethics in the treatment of chronic pain: the change of paradigms

Rev. Soc. Esp. Dolor. 2018; 25(5): 291-300 / DOI: 10.20986/resed.2018.3666/2018

Farmacologic adyuvants with saving effect of opioids in the perioperative period

Rev. Soc. Esp. Dolor. 2018; 25(5): 278-290 / DOI: 10.20986/resed.2018.3663/2018

Experience in two hospitals about the observation of pain responses in hospitalized preterm infants

Rev. Soc. Esp. Dolor. 2018; 25(5): 271-277 / DOI: 10.20986/resed.2018.3633/2017

Platelet-rich plasma in treating peripheral neuropathic pain. Preliminary report

Rev. Soc. Esp. Dolor. 2018; 25(5): 263-270 / DOI: 10.20986/resed.2017.3625/2017

Pain in the elderly and in patients with cognitive deficit. A DELPHI study

Rev. Soc. Esp. Dolor. 2018; 25(5): 251-262 / DOI: 10.20986/resed.2017.3621/2017

Chrono study: prevalence of breakthrough pain among patients with non-cancer chronic pain in Andalusia, Spain

Rev Soc Esp Dolor 2018; 25(4): 214-221 / DOI: 10.20986/resed.2017.3626/2017

Trial therapy on laterality and motor imagery and selective glenohumeral muscle activation in patients with massive rotator cuff tear: case series

Rev Soc Esp Dolor 2018; 25(4): 197-206 / DOI: 10.20986/resed.2017.3610/2017

Expenditure, prescription and consumption of analgesic drugs before and during the economic crisis

Rev Soc Esp Dolor 2018; 25(3): 155-162 / DOI: 10.20986/resed.2017.3609/2017

Sex and pain: sexual satisfaction and sexual function in a sample of patients with chronic, non-pelvic pain

Rev Soc Esp Dolor 2018; 25(3): 145-154 / DOI: 10.20986/resed.2018.3600/2017

Bibliometric analysis of the Journal of the Spanish Pain Society: 2007-2016

Rev Soc Esp Dolor 2018; 25(3):170-177 / DOI: 10.20986/resed.2018.3627/2017

Painometer v2®: a mobile application certified for monitoring patients with pain

Rev Soc Esp Dolor 2018; 25(2):112-120 / DOI: 10.20986/resed.2017.3555/2016

Analgesic efficacy of topical sevoflurane on wounds

Rev Soc Esp Dolor 2018; 25(2): 106-111 / DOI: 10.20986/resed.2017.3617/2017

Pharmacological management of acute postoperative pain in Spain. Data from the national survey by the Spanish Pain Society (SED)

Rev Soc Esp Dolor 2018; 25(2): 70-85 / DOI: 10.20986/resed.2017.3593/2017

Potential uses of Mirtazapine in palliative care beyond its antidepressant effect

Rev Soc Esp Dolor 2018; 25(1): 37-44 / DOI: 10.20986/resed.2017.3575/2017

Prevalence of pain in patients hospitalized in Metabolic Intensive Care Units with orotracheal intubation and under sedation, measured with the COMFORT scale

Rev Soc Esp Dolor 2018; 25(1): 7-12 / DOI: 10.20986/resed.2017.3581/2017

Pain management in cancer patients receiving radiotherapy: GORVAMUR study, a prospective, observational, epidemiological study

Rev Soc Esp Dolor 2017; 24(5): 241-255 / DOI: 10.20986/resed.2017.3570/2017

Epidural analgesia vs. surgical wound analgesia to control acute post-operative pain in open colon surgery

Rev Soc Esp Dolor 2017; 24(5): 234-240 / DOI: 10.20986/resed.2017.3559/2016

CAD-R. Chronic pain coping questionnaire: confirmatory factor analysis. Are there individual differences in gender, age and type of pain?

Rev Soc Esp Dolor 2017; 24(5): 224-233 / DOI: 10.20986/resed.2017.3558/2016

Intervention of manual motor skill exercises on pain and functionality in adults subjects with rheumatoid arthritis: case series

Rev Soc Esp Dolor 2017; 24(6): 294-303 / DOI: 10.20986/resed.2017.3576/2017

Characterization of chest pain in patients attending the emergency department of a high-complexity-level healthcare institution, during 2014-2015, in Medellín, Colombia

Rev Soc Esp Dolor 2017; 24(6): 288-293 / DOI: 10.20986/resed.2017.3571/2017

Chronic pain: relationship with prefrontal symptoms and perceived stress

Rev Soc Esp Dolor 2017; 24(4): 179-187 / DOI: 10.20986/resed.2017.3540/2016

The effectiveness of electrical spinal-cord stimulation in type i complex regional pain syndrome. A literature review

Rev Soc Esp Dolor 2017; 24(4): 169-178 / DOI: 10.20986/resed.2016.3501/2016

Paxiflas®: new FDT combination of tramadol/paracetamol for treating moderate to severe pain

Rev Soc Esp Dolor 2017; 24(2):59-67 / DOI: 10.20986/resed.2017.3565/2017

The predictive role of rumination and trait mindfulness in pain and negative mood after a sport injury: a longitudinal study

Rev Soc Esp Dolor 2017; 24(3):125-131 / DOI: 10.20986/resed.2017.3495/2016

Prevalence of breakthrough pain associated with chronic low back pain in Andalusia (COLUMBUS study)

Rev Soc Esp Dolor 2017; 24(3):116-124 / DOI: 10.20986/resed.2017.3548/2016

Effectiveness of hyaluronic acid intra-articular injections in treating knee osteoarthritis: results of a series of cases treated in a Pain Unit

Rev Soc Esp Dolor 2017; 24(2): 74-84 / DOI: 10.20986/resed.2016.3485/2016

Prescribing strong opioids in patients with non-cancer pain: a description of their characteristics in an area of primary healthcare assistance

Rev Soc Esp Dolor 2017; 24(1): 19-26 / DOI: 10.20986/resed.2016.3471/2016

Factors associated with pain intensity in Mexican patients hospitalized in postoperative period

Rev Soc Esp Dolor 2017; 24(1): 4-10 / DOI: 10.20986/resed.2016.3442/2016

Instrucciones para citar

García J, Berrocoso E, Micó J. Experimental models for pain evaluation in osteoarthritis. Rev Soc Esp Dolor 2021; 28(13): 18-30 / DOI: 1020986/resed20213872/2020


Descargar a un gestores de citas

Descargue la cita de este artículo haciendo clic en uno de los siguientes gestores de citas:

Métrica

Este artículo ha sido visitado 23421 veces.
Este artículo ha sido descargado 2 veces.

Estadísticas de Dimensions


Estadísticas de Plum Analytics

Ficha Técnica

Aceptado: 18/01/2021

Publicado: 03/02/2021


Compartir

Este artículo aun no tiene valoraciones.
Reader rating:
Rate this article:
Send by e-mail
© 2024 Revista de la Sociedad Española del Dolor
ISSN: 1134-8046   e-ISSN: 2254-6189

       Indexada en:
Política de Privacidad