Year 2022 / Volume 29 / Number 3

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Original

Single eco-guided intra-articular injection of hyaluronic acid in symptomatic coxarthrosis: retrospective study of the efficacy of two presentations

Rev. Soc. Esp. Dolor. 2022; 29(3): 140-148 / DOI: 10.20986/resed.2022.4014/2022

Agustín Miguel García, Carmen María Pérez, María Díaz, Milagros Yulimar, Carmen Mateo, Laura Rosa Bravo, Íñigo Hernández


ABSTRACT

Introduction: Ultrasound-guided viscosupplementation with hyaluronic acid in symptomatic hip osteoarthritis is widely used as a safe treatment with proven efficacy, although there is a lack of consensus on its use as routine practice. Few studies have compared the efficacy of two single injection products.
Objetive: To evaluate the efficacy in infiltrated patients with two single injection hyaluronic acids comparing Adant One® (A) at six months with annual Hyalone® (H).
Material and method: Restrospective observational study on a cohort of patients with symptomatic hip osteoarthritis, treated by ultrasound-guided intra-articular viscossuplementation with two types of single injection of hyaluronic acid. Its efficacy was evaluated according to the WOMAC and VAS scales at 6 and 12 months.
Results: 144 patients were treated with a single dose of A and 84 with H. At 6 months, those treated with A showed improvements in relation to pain reduction in the VAS (p < 0.001) and in the WOMAC pain (p = 0.003), as well as in global WOMAC (p = 0.027). There were no changes in WOMAC stiffness and function. At 12 months, those treated with H showed significant improvements in the VAS (p < 0.001) and global WOMAC (p = 0.010) parameters and in all their dimensions.
Conclusions: A single injection of annual H was more effective in improving pain and function of the hip with osteoarthritis at 1 year compared to A at 6 months. It is possible to establish annual viscossuplementation protocols for hip osteoarthritis with hyaluronic acid using H.



RESUMEN

Introducción: La viscosuplementación ecoguiada con ácido hialurónico en la coxartrosis sintomática se ha extendido como tratamiento seguro con eficacia demostrada, aunque con falta de consenso en su uso como práctica habitual. Pocos estudios han comparado la eficacia de dos productos de inyección única.
Objetivo: Evaluar la eficacia en pacientes infiltrados con dos ácidos hialurónicos de inyección única comparando Adant One® (A) a seis meses con Hyalone® (H) anual.
Material y método: Estudio observacional retrospectivo sobre cohorte de pacientes con coxartrosis sintomática, tratados mediante viscosuplementación intrarticular ecoguiada de cadera con dos tipos de inyección única de ácido hialurónico. Su eficacia fue evaluada de acuerdo con las escalas WOMAC y EVA a los 6 y 12 meses.
Resultados: Fueron tratados 144 pacientes con una dosis única de A y 84 con H. A los 6 meses aquellos tratados con A mostraron mejoras en relación con disminución del dolor en la EVA (p < 0,001) y en el WOMAC dolor (p = 0,003), así como en WOMAC global (p = 0,027). No hubo cambios en WOMAC rigidez y función. A los 12 meses los tratados con H mostraron mejorías en los parámetros EVA (p < 0,001) y WOMAC global (p = 0,010) y en todas sus dimensiones de manera significativa.
Conclusiones: Una inyección única de H anual fue más efectiva para mejorar el dolor y la funcionalidad de la cadera con artrosis a 1 año comparado con A semestral. Es posible establecer protocolos anuales de viscosuplementación para la artrosis de cadera con ácido hialurónico usando H.





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Bibliografía

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Instrucciones para citar

García A, Pérez C, Díaz M, Yulimar M, Mateo C, Bravo L, et all. Single eco-guided intra-articular injection of hyaluronic acid in symptomatic coxarthrosis: retrospective study of the efficacy of two presentations. Rev Soc Esp Dolor 2022; 29(3): 140-148 / DOI: 1020986/resed20224014/2022


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Ficha Técnica

Recibido: 27/08/2022

Aceptado: 20/12/2022

Prepublicado: 21/12/2022

Publicado: 26/01/2023

Tiempo de revisión del artículo: 85 días

Tiempo de prepublicación: 116 días

Tiempo de edición del artículo: 152 días


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