Year 2019 / Volume 26 / Number 1

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Special Article

Oxytocin and chronic pain in humans

Rev. Soc. Esp. Dolor. 2019; 26(1): 52-58 / DOI: 10.20986/resed.2018.3664/2018

Ximena Palacios Espinosa, Ana María Gómez Carvajal, Juan Sebastián Botero Meneses, Leonardo Palacios Sánchez


ABSTRACT

Oxytocin (OT) is a long known neuropeptide, and it's uses in clinical practice, mainly those regarding obstetrics have been thoroughly studied. However, there's been an increasing interest in identifying other roles OT plays in emotion, cognition, perception and higher cognitive processing. OT is also believed o have a mayor role in the physiology and physiopathology of pain. We have reviewed existent literature and current human studies on the relationship between OT and chronic pain. The present work compiles a significant number of research papers and may cast some light on a remarkably interesting and promising matter.



RESUMEN

La oxitocina (OT) es un neuropéptido conocido desde hace mucho tiempo, y sus usos en la práctica clínica, principalmente los relacionados con la obstetricia, se han estudiado en múltiples ocasiones. Sin embargo, ha habido un creciente interés en la identificación de otros roles que la OT pudiera tener en la emoción, la cognición, la percepción y otras funciones cognitivas superiores. También se cree que la OT es de gran importancia en la fisiología y la fisiopatología del dolor. Hemos revisado la literatura existente y los estudios actuales en humanos sobre la relación entre la OT y el dolor crónico. El presente trabajo compila un número significativo de trabajos de investigación y pudiera arrojar alguna luz sobre un asunto sumamente interesante y prometedor.


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Instrucciones para citar

Palacios Espinosa X, Gómez Carvajal A, Botero Meneses J, Palacios Sánchez L. Oxytocin and chronic pain in humans. Rev Soc Esp Dolor 2019; 26(1): 52-58 / DOI: 1020986/resed20183664/2018


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Recibido: 02/02/2018

Aceptado: 05/02/2018

Prepublicado: 16/03/2018

Publicado: 07/03/2019

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