Year 2021 / Volume 28 / Number 1

Cilinical Note

Parsonage-turner after rabies vaccination due to bat bite: case report

Rev. Soc. Esp. Dolor. 2021; 28(1): 57-61 / DOI: 10.20986/resed.2021.3832/2020

Leonardo Arce, Johan Fernando Cantor, Lina María Rodríguez


ABSTRACT

Introduction: Adult male patient who suffers a bat bite, after which rabies vaccine and tetanus toxoid are administered; later, he presents on the right upper limb severe motor, sensory and pain disorders. Initially a diagnostic challenge, after electrophysiological studies, Parsonage-Turner syndrome was considered. This case is relevant since the association between rabies vaccine and this syndrome has not been described.
Clinical case: Several diagnostic tests and images were performed, including ultrasound, magnetic resonance and electrophysiological studies, which confirmed the diagnosis of brachial neuritis (Parsonage-Turner syndrome). Even though the patient received surgical interventions with fasciotomies and neurolysis as well as multiple pharmacological pain management with strong opioids, neuromodulators, antidepressants and intrathecal pump medications, there was a 50 % decrease in pain symptoms and an impairment of their quality of life.
Conclusion: The case shows a Parsonage-Turner syndrome, a neurological disease with unknown etiology, with difficult diagnosis which can lead to chronic pain syndrome or unnecessary surgical procedures. This syndrome should be considered in emergency care and outpatient care due to its long-term consequences and the difficult management of chronic symptoms. There is a causal relationship reported in the literature with tetanus toxoid, but it was applied prior to symptoms; there are no reports of onset of symptoms after the rabies vaccine, which may generate a causal relationship in the future if new cases are found.



RESUMEN

Introducción: Paciente adulto masculino que consulta por mordedura de murciélago. Se realiza aplicación de vacuna antirrábica y toxoide tetánico, tras lo cual presenta alteraciones motoras, sensitivas y dolor de difícil manejo en el miembro superior derecho. Siendo un reto diagnóstico de manera inicial, posterior a estudios electrofisiológicos se consideró un síndrome de Parsonage-Turner. Este caso es relevante por la asociación de vacuna antirrábica no descrita en antecedentes de inmunización en revisiones previas.
Caso clínico: Se le realizaron varias pruebas diagnósticas e imágenes como ecografías, resonancia magnética y estudios electrofisiológicos los cuales confirmaron el diagnóstico de neuritis braquial (síndrome de Parsonage-Turner). El paciente recibió intervenciones quirúrgicas con fascitomías y neurólisis, además de múltiples manejos farmacológicos para dolor, incluyendo opioides fuertes, neuromoduladores, antidepresivos y medicamentos por bomba intratecal, con disminución solo del 50 % de los síntomas de dolor y afectación a su calidad de vida.
Conclusión: El caso nos muestra cómo el síndrome de Parsonage-Turner, una enfermedad neurológica con etiología desconocida, se puede cronificar en un síndrome doloroso al no tener un diagnóstico temprano o someter al paciente procedimientos no indicados. Este síndrome debe considerarse en la atención de urgencias y consulta externa por sus consecuencias a largo plazo y el difícil manejo de los síntomas crónicos. Hay una relación causal reportada en la literatura con el toxoide tetánico, pero este se aplicó previo a los síntomas; no hay referencias de inicio de síntomas posterior a la vacuna antirrábica, lo cual puede generar a futuro, una relación causal si se encontraran nuevos casos.





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Bibliografía

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Management of breakthrough pain associated with the cure of skin ulcers

Rev. Soc. Esp. Dolor. 2020; 27(2): 113-126 / DOI: 10.20986/resed.2020.3755/2019

Ethical problems in the management of pain. Qualitative study through open reflection interview

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Altruistic conduct: a behavioral strategy to decrease the perception of pain?

Rev. Soc. Esp. Dolor. 2020; 27(2): 76-77 / DOI: 10.20986/resed.2020.3806/2020

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Rev. Soc. Esp. Dolor. 2020; 27(2): 72-73 / DOI: 10.20986/resed.2020.3808/2020

The ozone paradigm in pain treatment

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Conventional radiofrequency for genicular nerves in treatment of knee osteoarthritis

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Effectiveness of the association of lacosamide in trigeminal neuralgia

Rev. Soc. Esp. Dolor. 2020; 27(1): 50-52 / DOI: 10.20986/resed.2019.3738/2019

Peripheral acting Mu opioid receptor antagonists in the treatment of the opioid-induced constipation: review

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Effectiveness of patient-controlled analgesia in acute and chronic pain after cardiac surgery: a prospective study

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Rev. Soc. Esp. Dolor. 2020; 27(1): 16-23 / DOI: 10.20986/resed.2020.3727/2019

Spinal stimulation modulated automatically. Evidence of closed stimulation systems: towards the pain pacemaker

Rev. Soc. Esp. Dolor. 2020; 27(1): 5-6 / DOI: 10.20986/resed.2020.3793/2020

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Rev. Soc. Esp. Dolor. 2020; 27(1): 3-4 / DOI: 10.20986/resed.2020.3792/2020

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Rev. Soc. Esp. Dolor. 2019; 26(6): 374-375 / DOI: 10.20986/resed.2019.3712/2018

Intratecal baclophene for the treatment of pain and spasticity in stiff man syndrome: a case report

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Key factors governing spinal cord opioid bioavailability in the management of acute pain

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Neurolytic procedures for pancreatic cáncer pain: a systematic review and a proposal for an algorithm treatment

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Correlation between pain and radiological parameters in patients older than 60 years of age with distal radius fracture

Rev. Soc. Esp. Dolor. 2019; 26(6): 324-330 / DOI: 10.20986/resed.2019.3720/2018

Connexins in chronic pain. A new target?

Rev. Soc. Esp. Dolor. 2019; 26(6): 322-323 / DOI: 10.20986/resed.2019.3785/2019

Celiac axis block in cancer pain: medicine of opportunity

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Pyoderma gangrenosum, undocumented complication of a spinal cord stimulation

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New strategies for postoperative pain control in tonsillectomy surgery. Is all that glitters gold?

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New ACP guidelines for non-radicular low back pain

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NMDA antagonism in the treatment of cluster headache

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Orofacial pain in the dental clinic

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Characterization of pain in patients with breast cancer attending the Oncology Unit of the San José Hospital

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Comparative analysis of vital signs in acutely hospitalized patients according to the pain intensity

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Erector spinae plane block for multiple unilateral ribs fractures.

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Dry needling and changes in muscular activity in subjects with myphastial trigger points: case series

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New indication of capsaicin 8 % patch: painful diabetic peripheral neuropathy

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Oxytocin and chronic pain in humans

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Psychosocial factors in chronic cancer pain: a Delphi study

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Micro RNAs: A new way for the management of neuropathic pain?

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Academic University training program of the Spanish Pain Society

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Dysphonia as side-effect dose-dependent during treatment with duloxetine

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Changes in intraocular pressure in patients with trigeminal neuralgia subject to radio frequency of the Gasserian ganglion

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Opinaudit study: clinical uses in breakthrough pain, is scientific evidence being followed up?

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Use of major opioids for control of pain in hospitalized patients

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Proctalgia and pudendal nerve entrapment: an association to know

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Consensus for the definition of post-mastectomy pain syndrome

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Radiofrequency thermal and splanchnics nerves block

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Implications of bioethics in the treatment of chronic pain: the change of paradigms

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Farmacologic adyuvants with saving effect of opioids in the perioperative period

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Experience in two hospitals about the observation of pain responses in hospitalized preterm infants

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Platelet-rich plasma in treating peripheral neuropathic pain. Preliminary report

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Pain in the elderly and in patients with cognitive deficit. A DELPHI study

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Chrono study: prevalence of breakthrough pain among patients with non-cancer chronic pain in Andalusia, Spain

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Expenditure, prescription and consumption of analgesic drugs before and during the economic crisis

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Sex and pain: sexual satisfaction and sexual function in a sample of patients with chronic, non-pelvic pain

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Bibliometric analysis of the Journal of the Spanish Pain Society: 2007-2016

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Painometer v2®: a mobile application certified for monitoring patients with pain

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Analgesic efficacy of topical sevoflurane on wounds

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Potential uses of Mirtazapine in palliative care beyond its antidepressant effect

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Epidural analgesia vs. surgical wound analgesia to control acute post-operative pain in open colon surgery

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Prevalence of breakthrough pain associated with chronic low back pain in Andalusia (COLUMBUS study)

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Arce L, Cantor J, Rodríguez L. Parsonage-turner after rabies vaccination due to bat bite: case report. Rev Soc Esp Dolor 2021; 28(1): 57-61 / DOI: 1020986/resed20213832/2020


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Recibido: 01/07/2020

Aceptado: 03/03/2021

Prepublicado: 04/03/2021

Publicado: 17/03/2021

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